Human Clusterin Protein BP004373 Syd Labs
Human Clusterin Protein (CLN-HM101)
Human Clusterin Protein BP004373 Syd Labs
Human Clusterin Protein (CLN-HM101)

Human Clusterin Protein C-His Tag | Syd Labs BP004373

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Human Clusterin Protein BP004373 Syd Labs

Human Clusterin Protein C-His Tag | Syd Labs BP004373

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(悉得）Syd Labs 货号：BP004373 Human Clusterin Protein with the C-His Tag (人 Clusterin 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Asp23-Glu449.

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Syd Labs, Inc.
SKU： BP004373 分类： ,

产品参数

货号 BP004373
产品名称Human Clusterin Protein C-His Tag | Syd Labs BP004373
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 Clusterin; Apolipoprotein J; Apo-J; Clustrin; SGP-2; Msgp-2; CLU; AAG4; APOJ; CLI; KUB1; SP-40; TRPM2; CLI; CLU1; CLU2; KUB1; NA1/NA2; KUB1SGP2; MGC24903
物种 Human
来源 The recombinant Human Clusterin Protein, (amino acids Asp23-Glu449) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-His
生物素化 no
确定序列 Asp23-Glu449
分子量 The recombinant Human Clusterin protein with the His tag at the C-terminus has a predicted MW of 51.2 kDa. The protein migrates to 38-41 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human Clusterin protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-Clusterin Antibody protein with the C-hFc tag with the EC50 of 49.2 ng/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human Clusterin Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human Clusterin Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human Clusterin Protein performance should be determined experimentally by the investigator.
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文献

BP004373: Human Clusterin Protein with the C-His Tag (人 Clusterin 蛋白 C-His 标签)

 

Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone, normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers. It plays important roles in protein homeostasis/proteostasis, inhibition of cell death pathways, and modulation of pro-survival signalling and transcriptional networks. Changes in the CLU gene locus are highly associated with Alzheimer disease, and many therapy-resistant cancers over-express CLU.

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