Human CD96/TACTILE Protein BP004317 Syd Labs
Human CD96/TACTILE Protein (CD9-HM196)
Human CD96/TACTILE Protein (CD9-HM196)
Human CD96/TACTILE Protein (CD9-HM196)
Human CD96/TACTILE Protein BP004317 Syd Labs
Human CD96/TACTILE Protein (CD9-HM196)
Human CD96/TACTILE Protein (CD9-HM196)
Human CD96/TACTILE Protein (CD9-HM196)

Human CD96/TACTILE Protein C-His Tag | Syd Labs BP004317

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Human CD96/TACTILE Protein BP004317 Syd Labs

Human CD96/TACTILE Protein C-His Tag | Syd Labs BP004317

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(悉得）Syd Labs 货号：BP004317 Human CD96/TACTILE Protein with the C-His Tag (人 CD96/TACTILE 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Val22-Met503.

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Syd Labs, Inc.
SKU： BP004317 分类： ,

产品参数

货号 BP004317
产品名称Human CD96/TACTILE Protein C-His Tag | Syd Labs BP004317
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 CD96 molecule; CD96; DKFZp667E2122; TACTILE
物种 Human
来源 The recombinant Human CD96/TACTILE Protein, (amino acids Val22-Met503) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Accession P40200-2
产品标签 C-His
生物素化 no
确定序列 Val22-Met503
分子量 The recombinant Human CD96/TACTILE protein with the His tag at the C-terminus has a predicted MW of 54.7 kDa. Due to glycosylation, the protein migrates to 115-130 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Anti-CD96 Antibody protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human CD96 protein with the C-His tag with the EC50 of 28.8 ng/ml determined by ELISA (QC Test). The affinity constant of 0.958 uM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human CD96/TACTILE Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1EU per ug by the LAL method.
运输 The recombinant Human CD96/TACTILE Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Human CD96/TACTILE Protein performance should be determined experimentally by the investigator.
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文献

BP004317: Human CD96/TACTILE Protein with the C-His Tag (人 CD96/TACTILE 蛋白 C-His 标签)

 

The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.

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