Human CCR8 Protein C-hFc Tag | Syd Labs BP003660
(悉得)Syd Labs 货号:BP003660 Human CCR8 Protein with the C-hFc Tag (人 CCR8 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met1-Lys35.
产品参数
| 货号 | BP003660 |
|---|---|
| 产品名称 | Human CCR8 Protein C-hFc Tag | Syd Labs BP003660 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Human |
| 来源 | The recombinant Human CCR8 Protein, (amino acids Met1-Lys35) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | P51685-1 |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | Met1-Lys35 |
| 分子量 | The recombinant Human CCR8 protein with the hFc tag at the C-terminus has a predicted MW of 30.62 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human-CCR8 protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Anti-CCR8 Antibody protein with the C-hFc tag with the EC50 of 29.6 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human CCR8 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human CCR8 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Human CCR8 Protein performance should be determined experimentally by the investigator. |
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文献
BP003660: Human CCR8 Protein with the C-hFc Tag (人 CCR8 蛋白 C-hFc 标签)
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.
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