FADD Rabbit mAb
GIG3; IMD90; MORT1
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| 货号 | A19049 |
|---|---|
| 产品名称 | FADD Rabbit mAb |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | GIG3; IMD90; MORT1 |
| 基因名称 | FADD |
| 蛋白名 | FADD |
| Uniprot/Swissprot ID | Q13158 |
| Entrez GeneID | 8772 |
| 克隆号 | ARC0415 |
| 克隆性 | Monoclonal |
| 来源 | Rabbit |
| 反应性 | Human |
| 偶联 | Unconjugated |
| 注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
描述
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
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