Cynomolgus BST2 Protein N-His Tag | Syd Labs BP003909
(悉得）Syd Labs 货号：BP003909 Cynomolgus BST2 Protein with the N-His Tag (食蟹猴 BST2 蛋白 N-His 标签) is expressed from HEK293 with His tag at the N-Terminus.It contains Ile49-Ser163.
产品参数
| 货号 | BP003909 |
|---|---|
| 产品名称 | Cynomolgus BST2 Protein N-His Tag | Syd Labs BP003909 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Cynomolgus |
| 来源 | The recombinant Cynomolgus BST2 Protein, (amino acids Ile49-Ser163) fused with a His tag at the N-terminus, was produced in HEK 293 cells. |
| Accession | XP_005588438.1 |
| 产品标签 | N-His |
| 生物素化 | no |
| 确定序列 | Ile49-Ser163 |
| 分子量 | The recombinant Cynomolgus BST2 protein with the His tag at the N-terminus has a predicted MW of 13.78 kDa. Due to glycosylation, the protein migrates to 15-30 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Cynomolgus BST2 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Cynomolgus BST2 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Cynomolgus BST2 Protein performance should be determined experimentally by the investigator. |
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文献
BP003909: Cynomolgus BST2 Protein with the N-His Tag (食蟹猴 BST2 蛋白 N-His 标签)
Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor.
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