Cynomolgus ALK-1/ACVRL1 Protein C-His Tag | Syd Labs BP003410
(悉得）Syd Labs 货号：BP003410 Cynomolgus ALK-1/ACVRL1 Protein with the C-His Tag (食蟹猴 ALK-1/ACVRL1 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Asp22-Gln118.
产品参数
| 货号 | BP003410 |
|---|---|
| 产品名称 | Cynomolgus ALK-1/ACVRL1 Protein C-His Tag | Syd Labs BP003410 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Cynomolgus |
| 来源 | The recombinant Cynomolgus ALK-1/ACVRL1 Protein, (amino acids Asp22-Gln118) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | XP_005570958.1 |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Asp22-Gln118 |
| 分子量 | The recombinant Cynomolgus ALK-1/ACVRL1 protein with the His tag at the C-terminus has a predicted MW of 11.86 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| 形式 | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Cynomolgus ALK-1/ACVRL1 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Cynomolgus ALK-1/ACVRL1 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Cynomolgus ALK-1/ACVRL1 Protein performance should be determined experimentally by the investigator. |
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文献
BP003410: Cynomolgus ALK-1/ACVRL1 Protein with the C-His Tag (食蟹猴 ALK-1/ACVRL1 蛋白 C-His 标签)
Activin receptor-like kinase 1 (ALK1)-mediated endothelial cell signalling in response to bone morphogenetic protein 9 (BMP9) and BMP10 is of significant importance in cardiovascular disease and cancer. Structural analyses reveal a tripartite recognition mechanism that defines BMP9 and BMP10 specificity for ALK1, and predict that crossveinless 2 is not an inhibitor of BMP9, which is confirmed by experimental evidence.
请记住我们的产品信息: 食蟹猴 ALK-1/ACVRL1 蛋白 （C-His 标签）BP003410 Syd Labs（Cynomolgus ALK-1/ACVRL1 Protein with the C-His Tag）.
