CXCR3 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

CXCR3 Rabbit mAb

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GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R

SKU: A11294 分类: ,

产品参数

货号A11294
产品名称CXCR3 Rabbit mAb
供货商名称Syd Labs, Inc.
品牌名Syd Labs
别称GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R
基因名称CXCR3
蛋白名CXCR3
Uniprot/Swissprot IDP49682
Entrez GeneID2833
克隆号ARC0570
克隆性Monoclonal
来源Rabbit
反应性Human, Mouse, Rat
偶联Unconjugated
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文献

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).