Cleaved PARP1 p25 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Cleaved PARP1 p25 Rabbit mAb

In stock

一键复制

PARP; PARS; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1; Poly-PARP

SKU: A19612 分类: ,

产品参数

货号A19612
产品名称Cleaved PARP1 p25 Rabbit mAb
供货商名称Syd Labs, Inc.
品牌名Syd Labs
别称PARP; PARS; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1; Poly-PARP
基因名称PARP1
蛋白名PARP1
Uniprot/Swissprot IDP09874
Entrez GeneID142
克隆号ARC0091
克隆性Monoclonal
来源Rabbit
反应性Human, Mouse
偶联Unconjugated
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文献

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.