Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein C-His-Avi Tag | Syd Labs BP005638
(悉得）Syd Labs 货号：BP005638 Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein with the C-His-Avi Tag (生物素化人 TRAIL R2/DR5/TNFRSF10B 蛋白 C-His-Avi 标签) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ile56-Glu182.
产品参数
| 货号 | BP005638 |
|---|---|
| 产品名称 | Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein C-His-Avi Tag | Syd Labs BP005638 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD262; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER |
| 物种 | Human |
| 来源 | The recombinant Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein, (amino acids Ile56-Glu182) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | O14763-1 |
| 产品标签 | C-His-Avi |
| 生物素化 | yes |
| 确定序列 | Ile56-Glu182 |
| 分子量 | The recombinant Biotinylated Human TRAIL R2/DR5/TNFRSF10B protein with the His-Avi tag at the C-terminus has a predicted MW of 17.2 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Bis-Tris PAGE result. |
| 活性 | Immobilized recombinant Biotinylated Human TRAIL R2 protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Anti-TRAIL R2 Antibody protein with the C-hFc tag with the EC50 of 5.8 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP005638: Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein with the C-His-Avi Tag (生物素化人 TRAIL R2/DR5/TNFRSF10B 蛋白 C-His-Avi 标签)
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
请记住我们的产品信息: 生物素化人 TRAIL R2/DR5/TNFRSF10B 蛋白 （C-His-Avi 标签）BP005638 Syd Labs（Biotinylated Human TRAIL R2/DR5/TNFRSF10B Protein with the C-His-Avi Tag）.