Biotinylated Human LILRA4/CD85g Protein C-His-Avi Tag | Syd Labs BP004168
(悉得）Syd Labs 货号：BP004168 Biotinylated Human LILRA4/CD85g Protein with the C-His-Avi Tag (生物素化人 LILRA4/CD85g 蛋白 C-His-Avi 标签) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu24-Asn446.
产品参数
| 货号 | BP004168 |
|---|---|
| 产品名称 | Biotinylated Human LILRA4/CD85g Protein C-His-Avi Tag | Syd Labs BP004168 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD85g; ILT7; ILT-7; ILT7MGC129598; LILRA4; MGC129597 |
| 物种 | Human |
| 来源 | The recombinant Biotinylated Human LILRA4/CD85g Protein, (amino acids Glu24-Asn446) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-His-Avi |
| 生物素化 | yes |
| 确定序列 | Glu24-Asn446 |
| 分子量 | The recombinant Biotinylated Human LILRA4/CD85g protein with the His-Avi tag at the C-terminus has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Biotinylated Human LILRA4/CD85g Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Biotinylated Human LILRA4/CD85g Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Biotinylated Human LILRA4/CD85g Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004168: Biotinylated Human LILRA4/CD85g Protein with the C-His-Avi Tag (生物素化人 LILRA4/CD85g 蛋白 C-His-Avi 标签)
LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
请记住我们的产品信息: 生物素化人 LILRA4/CD85g 蛋白 （C-His-Avi 标签）BP004168 Syd Labs（Biotinylated Human LILRA4/CD85g Protein with the C-His-Avi Tag）.
