Biotinylated Cynomolgus Siglec-10 Protein BP003123 Syd Labs
Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B)
Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B)
Biotinylated Cynomolgus Siglec-10 Protein BP003123 Syd Labs
Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B)
Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B)

Biotinylated Cynomolgus Siglec-10 Protein C-His-Avi Tag | Syd Labs BP003123

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Proteinase K Solution, PCR Grade (20 mg/ml): MB112 Syd Labs Proteinase K Solution, PCR Grade (20 mg/ml)
Biotinylated Cynomolgus Siglec-10 Protein BP003123 Syd Labs

Biotinylated Cynomolgus Siglec-10 Protein C-His-Avi Tag | Syd Labs BP003123

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Syd Labs 货号：BP003123 Biotinylated Cynomolgus Siglec-10 Protein with the C-His-Avi Tag is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Asn552.

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SKU： BP003123 分类： ,

产品参数

货号 BP003123
产品名称Biotinylated Cynomolgus Siglec-10 Protein C-His-Avi Tag | Syd Labs BP003123
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
物种 Cynomolgus
来源 The recombinant Biotinylated Cynomolgus Siglec-10 Protein, (amino acids Thr17-Asn552) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-His
生物素化 yes
确定序列 Thr17-Asn552
分子量 The recombinant Biotinylated Cynomolgus Siglec-10 protein with the His-Avi tag at the C-terminus has a predicted MW of 61.71 kDa. Due to glycosylation, the protein migrates to 72-82 kDa based on Tris-Bis PAGE result.
Form Liquid
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Biotinylated Cynomolgus Siglec-10 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Biotinylated Cynomolgus Siglec-10 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
注意事项 Conditions of optimal recombinant Biotinylated Cynomolgus Siglec-10 Protein performance should be determined experimentally by the investigator.
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文献

BP003123: Biotinylated Cynomolgus Siglec-10 Protein with the C-His-Avi Tag

Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
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