APEX1/APE1 Rabbit mAb
APE; APX; APE1; APEN; APEX; HAP1; REF1
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| 货号 | A11238 |
|---|---|
| 产品名称 | APEX1/APE1 Rabbit mAb |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | APE; APX; APE1; APEN; APEX; HAP1; REF1 |
| 基因名称 | APEX1 |
| 蛋白名 | APEX1 |
| Uniprot/Swissprot ID | P27695 |
| Entrez GeneID | 328 |
| 克隆号 | ARC0556 |
| 克隆性 | Monoclonal |
| 来源 | Rabbit |
| 反应性 | Human, Mouse, Rat |
| 偶联 | Unconjugated |
| 注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
描述
The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.
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