Androgen Receptor Rabbit mAb (A19611)
(悉得）Syd Labs Androgen Receptor Rabbit mAb (Catalog Number: A19611) gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain.
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| 货号 | A19611 |
|---|---|
| 产品名称 | Androgen Receptor Rabbit mAb (A19611) |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | KD; AIS; AR8; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA |
| 基因名称 | AR |
| 蛋白名 | AR |
| Uniprot/Swissprot ID | P10275 |
| Entrez GeneID | 367 |
| 克隆号 | ARC0090 |
| 克隆性 | Monoclonal |
| 来源 | Rabbit |
| 反应性 | Human, Mouse, Rat |
| 偶联 | Unconjugated |
| 注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
描述
A19611: Androgen Receptor Rabbit mAb
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy’s disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Information about Androgen Receptor Rabbit mAb (A19611)
Immunogen：A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Androgen Receptor (P10275).
Sequence：MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAH
Gene ID：367
Swiss prot：P10275
Synonyms：KD; AIS; AR8; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; Androgen Receptor
Calculated MW：99kDa
Observed MW：110kDa
Please remember our product information: Androgen Receptor Rabbit mAb (Catalog Number: A19611) (悉得）Syd Labs
