XPD/ERCC2 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

XPD/ERCC2 Rabbit mAb

In stock

EM9; TTD; XPD; TTD1; COFS2; TFIIH

SKU: A19241 分类: ,
货号 A19241
产品名称XPD/ERCC2 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 EM9; TTD; XPD; TTD1; COFS2; TFIIH
基因名称 ERCC2
蛋白名 ERCC2
Uniprot/Swissprot ID P18074
Entrez GeneID 2068
克隆号 ARC2401
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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描述

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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