TNNC1 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

TNNC1 Rabbit mAb

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TNC; TN-C; TNNC; CMD1Z; CMH13

SKU: A3816 分类: ,

产品参数

货号 A3816
产品名称TNNC1 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 TNC; TN-C; TNNC; CMD1Z; CMH13
基因名称 TNNC1
蛋白名 TNNC1
Uniprot/Swissprot ID P63316
Entrez GeneID 7134
克隆号 ARC0840
克隆性 Monoclonal
来源 Rabbit
反应性 Mouse, Rat
偶联 Unconjugated
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文献

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.