TAK1 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

TAK1 Rabbit mAb

In stock

CSCF; FMD2; TAK1; MEKK7; TGF1a

SKU: A19077 分类: ,
货号 A19077
产品名称TAK1 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 CSCF; FMD2; TAK1; MEKK7; TGF1a
基因名称 MAP3K7
蛋白名 MAP3K7
Uniprot/Swissprot ID O43318
Entrez GeneID 6885
克隆号 ARC0413
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse
偶联 Unconjugated
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描述

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

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