SUN2 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

SUN2 Rabbit mAb

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UNC84B; rab5IP

SKU: A19782 分类: ,

产品参数

货号 A19782
产品名称SUN2 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 UNC84B; rab5IP
基因名称 SUN2
蛋白名 SUN2
Uniprot/Swissprot ID Q9UH99
Entrez GeneID 25777
克隆号 ARC2311
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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文献

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a ‘bridge’ across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).