Sorbitol Dehydrogenase Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Sorbitol Dehydrogenase Rabbit mAb

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RDH; SDH; XDH; SORD1; SORDD; HEL-S-95n

SKU: A21952 分类: ,

产品参数

货号 A21952
产品名称Sorbitol Dehydrogenase Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 RDH; SDH; XDH; SORD1; SORDD; HEL-S-95n
基因名称 SORD
蛋白名 SORD
Uniprot/Swissprot ID Q00796
Entrez GeneID 6652
克隆号 ARC53945
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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文献

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.