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化合物, 抑制剂，激活剂，拮抗剂和激动剂DEL-22379
DEL-22379 (CAS No.: 181223-80-3), a potent and selective ERK Dimerization inhibitor. DEL-22379 inhibits ERK Dimerization without affecting ERK phosphorylation, forestalls tumorigenesis driven by RAS-ERK pathway oncogenes. Nearly 50%…
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
BEC hydrochloride
BEC hydrochloride (CAS No.: 222638-67-7), a slow-binding and competitive Arginase II inhibitor. >98% Purity.
Synonyms: BEC, BEC HCl, Arginase II inhibitor
For Research Use Only.
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
RTA-408 (Omaveloxolone)
RTA-408 (CAS No.: 1474034-05-3), a Novel Synthetic Triterpenoid That Binds to Kelch-like ECH-associated Protein 1 (Keap1) and Attenuate Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Degradation. >99% Purity.
Synonyms: Omaveloxolone, Nuclear…
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
ND-646
ND-646 (CAS No.: 1434639-57-2), an Orally Bioavailable and Steric Inhibitor of Acetyl-CoA Carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for Recombinant hACC1 and hACC2, Respectively. >99% Purity.
Synonyms:…
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
Batefenterol (GSK-961081)
GSK-961081 (Batefenterol, TD-5959) (CAS No.: 743461-65-6), Novel Muscarinic Receptor Antagonist and β2
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
Etoposide phosphate (BMY-40481)
Etoposide Phosphate (BMY-40481) (CAS No.: 117091-64-2), potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands.
Synonyms: topoisomerase II inhibitor, BMY-40481, BMY40481, BMY 40481
For…
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
Glumetinib (SCC244)
Glumetinib (SCC244) is a highly selective, orally bioavailable, ATP-competitive c-Met inhibitor with an IC50 of 0.42 nM. Glumetinib has greater than 2400-fold selectivity for c-Met over those 312 kinases…
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
KB-0742 dihydrochloride (KB0742)
KB0742(KB-0742, KB 0742) (CAS No.: 2416874-75-2), an orally bioavailable, potent and selective CDK9 inhibitor with an IC50 of 6 nM, highly selective against other CDKs (>60 fold). 99% Chem and…
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
GSK046 (GSK-046, IBET-BD2)
GSK046 (iBET-BD2, GSK 046, GSK-046) (CAS No.: 2474876-09-8), a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98…
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
BI-3406
BI-3406 (CAS No.: 2230836-55-0), a highly potent, selective, and orally bioavailable inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM.
Synonyms:…
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化合物, 抑制剂，激活剂，拮抗剂和激动剂
Giredestrant (GDC-9545)
Giredestrant(GDC-9545, CAS No.: 1953133-47-5), an orally active and selective estrogen receptor antagonist, potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding domain….
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抗体, 科研级生物类似抗体
Volociximab Biosimilar, Anti-human Integrin α5β1 Monoclonal Antibody
The cheapest research grade volociximab biosimilar (anti-human integrin α5β1 monoclonal antibody, mAb) for ELISA, neutralization, in vivo functional assays such as bioanalytical PK and ADA assays, and those in…
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