SARS-CoV-2 Spike S1 Rabbit Monoclonal Antibody
Monoclonal SARS-CoV-2 spike antibody as the human IgG antibody positive control for serological assays for qualitative detection or semi-quantitative measurement of human IgG antibodies specific to the SARS-CoV-2 spike protein, S1 subunit in serum or plasma.
产品参数
| 货号 | PA0071 |
|---|---|
| 产品名称 | SARS-CoV-2 Spike S1 Rabbit Monoclonal Antibody |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 克隆号 | 5A8. |
| 特异性 | The monoclonal SARS-CoV-2 (2019-nCoV) spike S1 antibody binds to SARS-CoV-2 and SARS-CoV spike RBD, S protein, and S1 subunit. |
| 抗体形式 | 1 mg/ml in PBS, pH 7.4. |
| 纯度 | >95% by SDS-PAGE under reducing conditions. |
| 运输 | The anti-SARS-CoV-2 (2019-nCoV) spike S1 rabbit monoclonal antibody is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
PA007140: SARS-CoV-2 Spike S1 Rabbit Monoclonal Antibody (Clone # 5A8)
Rabbit IgG Monoclonal Antibody.
The anti-SARS-CoV-2 (2019-nCoV) spike S1 rabbit monoclonal antibody (S protein antibody, spike S1 antibody) was produced in mammalian cells.
Background
The receptor binding domain (RBD) in the S1 subunit of the SARS-CoV-2 (2019-nCoV) spike (S) glycoprotein plays the most important roles in viral attachment, fusion and entry. The SARS-CoV and SARS-CoV-2 S proteins mediate viral entry into host cells by binding to a host receptor, angiotensin-converting enzyme 2 (ACE2), through the receptor-binding domain (RBD) in the S1 subunit, and then fusing the viral and host membranes through the S2 subunit. The ACE2-binding affinity of the Spike RBD of SARS-CoV-2 is 10- to 20-fold higher than that of SARS-CoV.
The SARS-CoV-2 S protein, especially its S1 subunit and RBD, has become a popular target of antibodies for diagnostics test, and proteins and antibodies for therapeutic drugs.
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