SARS-COV-2 Spike S1 (Deltacron) Protein (COV-VM1SD)
(悉得）Syd Labs SARS-COV-2 Spike S1 (Deltacron) Protein (COV-VM1SD) (catalog No. COV-VM1SD) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln14-Arg683(T19R, A27S, T95I, G142D, EFR156G, NL211I, INS214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H). Alanine substitutions (R683A) are introduced to stabilize the trimeric prefusion state of SARS-COV-2 Spike S1(Deltacron) Protein and abolish the furin cleavage site, respectively.
产品参数
| 货号 | COV-VM1SD |
|---|---|
| 产品名称 | SARS-COV-2 Spike S1 (Deltacron) Protein (COV-VM1SD) |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | SARS-COV-2 |
| 来源 | HEK293 |
| Accession | QHD43416.1 |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Gln14-Arg683(T19R, A27S, T95I, G142D, EFR156G, NL211I, INS214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H) |
| 分子量 | The protein has a predicted MW of 73.94 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| 形式 | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | Shipped with dry ice. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
COV-VM1SD: SARS-COV-2 Spike S1 (Deltacron) Protein (COV-VM1SD)
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Please remember our product information: SARS-COV-2 Spike S1 (Deltacron) Protein (COV-VM1SD) catalog number: COV-VM1SD (悉得）Syd Labs