RNF8 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

RNF8 Rabbit mAb

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hRNF8

SKU: A22524 分类: ,

产品参数

货号 A22524
产品名称RNF8 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 hRNF8
基因名称 RNF8
蛋白名 RNF8
Uniprot/Swissprot ID O76064
Entrez GeneID 9025
克隆号 ARC58373
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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文献

The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.