RNF7 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

RNF7 Rabbit mAb

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SAG; ROC2; rbx2; CKBBP1

SKU: A21137 分类: ,

产品参数

货号 A21137
产品名称RNF7 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 SAG; ROC2; rbx2; CKBBP1
基因名称 RNF7
蛋白名 RNF7
Uniprot/Swissprot ID Q9UBF6
Entrez GeneID 9616
克隆号 ARC3065
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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文献

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.