Rat IL-22R alpha 1 Protein C-hFc Tag | Syd Labs BP003313
(悉得)Syd Labs 货号:BP003313 Rat IL-22R alpha 1 Protein with the C-hFc Tag (大鼠 IL-22R alpha 1 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains His16-Ala228.
产品参数
| 货号 | BP003313 |
|---|---|
| 产品名称 | Rat IL-22R alpha 1 Protein C-hFc Tag | Syd Labs BP003313 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Rat |
| 来源 | The recombinant Rat IL-22R alpha 1 Protein, (amino acids His16-Ala228) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | His16-Ala228 |
| 分子量 | The recombinant Rat IL-22R alpha 1 protein with the hFc tag at the C-terminus has a predicted MW of 51.08 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human IL-22 protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Rat IL-22R alpha 1 protein with the C- hFc Tag with the EC50 of 30.4 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Rat IL-22R alpha 1 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Rat IL-22R alpha 1 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Rat IL-22R alpha 1 Protein performance should be determined experimentally by the investigator. |
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文献
BP003313: Rat IL-22R alpha 1 Protein with the C-hFc Tag (大鼠 IL-22R alpha 1 蛋白 C-hFc 标签)
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3.
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