RAIDD/CRADD Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

RAIDD/CRADD Rabbit mAb

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MRT34; RAIDD

SKU: A8664 分类: ,

产品参数

货号 A8664
产品名称RAIDD/CRADD Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 MRT34; RAIDD
基因名称 CRADD
蛋白名 CRADD
Uniprot/Swissprot ID P78560
Entrez GeneID 8738
克隆号 ARC1771
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Rat
偶联 Unconjugated
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文献

This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.