Rad18 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Rad18 Rabbit mAb

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RNF73

SKU: A4339 分类: ,

产品参数

货号 A4339
产品名称Rad18 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 RNF73
基因名称 RAD18
蛋白名 RAD18
Uniprot/Swissprot ID Q9NS91
Entrez GeneID 56852
克隆号 ARC1058
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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文献

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.