Phospho-Cdc6-S54 Rabbit mAb

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Phospho-Cdc6-S54 Rabbit mAb

In stock

CDC18L; HsCDC6; MGORS5; HsCDC18

SKU: AP1153 分类: ,
货号 AP1153
产品名称Phospho-Cdc6-S54 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 CDC18L; HsCDC6; MGORS5; HsCDC18
基因名称 CDC6
蛋白名 CDC6
Uniprot/Swissprot ID Q99741
Entrez GeneID 990
克隆号 ARC1693
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse
偶联 Unconjugated
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描述

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

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