Phospho-Cardiac Troponin I (TNNI3)-S23/S24 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-Cardiac Troponin I (TNNI3)-S23/S24 Rabbit mAb

In stock

CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF

SKU: AP1400 分类: ,
货号 AP1400
产品名称Phospho-Cardiac Troponin I (TNNI3)-S23/S24 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF
基因名称 TNNI3
蛋白名 TNNI3
Uniprot/Swissprot ID P19429
Entrez GeneID 7137
克隆号 ARC56024
克隆性 Monoclonal
来源 Rabbit
反应性 Human
偶联 Unconjugated
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
线下下单 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com

描述

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19.

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