PAK1 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

PAK1 Rabbit mAb

In stock

IDDMSSD; p65-PAK; PAKalpha; alpha-PAK

SKU: A19608 分类: ,
货号 A19608
产品名称PAK1 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 IDDMSSD; p65-PAK; PAKalpha; alpha-PAK
基因名称 PAK1
蛋白名 PAK1
Uniprot/Swissprot ID Q13153
Entrez GeneID 5058
克隆号 ARC0087
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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描述

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Mutations in this gene have been associated with macrocephaly, seizures, and speech delay. Overexpression of this gene is also reported in many cancer types, and particularly in breast cancer. Alternative splicing results in multiple transcript variants.

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