Background Information:

A potent, selective and orally bioavailable mTOR inhibitor currently in clinical trial.

Reference:

1. N. Cayarol, et al., Critical roles for mTORC2- and
rapamycin-insensitive mTORC1-complexes in growth and survival of
BCR-ABL-expressing leukemic cells, PNAS, 2010 107 (28) 12469-12474.*
Confirmed by a quantitative elemental analysis.

APIM050213: OSI-027

CAS No.: 936890-98-1.
Molecular Formula: C₂₁H₂₂N₆O₃ ?1.3CF₃CO₂H.
Molecular Weight: 554.1.
Purity: 99% (HPLC at 220 nm).
QC: HPLC-MS, ¹HNMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.