OGDH Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

OGDH Rabbit mAb

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E1k; E1o; KGD1; OGDC; AKGDH; OGDH2; OGDHD; OGDH-E1

SKU: A22163 分类: ,

产品参数

货号 A22163
产品名称OGDH Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 E1k; E1o; KGD1; OGDC; AKGDH; OGDH2; OGDHD; OGDH-E1
基因名称 OGDH
蛋白名 OGDH
Uniprot/Swissprot ID Q02218
Entrez GeneID 4967
克隆号 ARC55379
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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文献

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.