Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein C-hFc Tag | Syd Labs BP003834

Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein BP003834 Syd Labs

Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein C-hFc Tag | Syd Labs BP003834

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(悉得)Syd Labs 货号:BP003834 Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein with the C-hFc Tag (小鼠整合素 alpha V beta 3 (ITGAV&ITGB3) 异二聚体蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail.

SKU: BP003834 分类: ,

产品参数

货号 BP003834
产品名称Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein C-hFc Tag | Syd Labs BP003834
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
物种 Mouse
来源 The recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, (amino acids Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
产品标签 C-hFc
生物素化 no
确定序列 Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail
分子量 The recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer protein with the hFc tag at the C-terminus has a predicted MW of 131.48 kDa(ITGAV)&101.58 kDa(ITGB3). Due to enzyme lysis and glycosylation, the protein migrates to 110-135 kDa and 50-60 kDa based on Tris-Bis PAGE result.
活性 The affinity constant of 3.37 nM as determined in SPR assay (Biacore T200).
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein performance should be determined experimentally by the investigator.
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文献

BP003834: Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein with the C-hFc Tag (小鼠整合素 alpha V beta 3 (ITGAV&ITGB3) 异二聚体蛋白 C-hFc 标签)

 

ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.

请记住我们的产品信息: 小鼠整合素 alpha V beta 3 (ITGAV&ITGB3) 异二聚体蛋白 (C-hFc 标签)BP003834 Syd Labs(Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein with the C-hFc Tag).