Mouse BACE-1 Protein C-His Tag | Syd Labs BP004140

Mouse BACE-1 Protein BP004140 Syd Labs

Mouse BACE-1 Protein C-His Tag | Syd Labs BP004140

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(悉得)Syd Labs 货号:BP004140 Mouse BACE-1 Protein with the C-His Tag (小鼠 BACE-1 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Thr22-Thr457.

SKU: BP004140 分类: ,

产品参数

货号 BP004140
产品名称Mouse BACE-1 Protein C-His Tag | Syd Labs BP004140
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 Beta-secretase 1; ASP2; Asp 2; BACE1; BACE; FLJ90568; HSPC104; KIAA1149; Memapsin-2; BACE-1; EC 3.4.23; EC 3.4.23.46
物种 Mouse
来源 The recombinant Mouse BACE-1 Protein, (amino acids Thr22-Thr457) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Accession P56818
产品标签 C-His
生物素化 no
确定序列 Thr22-Thr457
分子量 The recombinant Mouse BACE-1 protein with the His tag at the C-terminus has a predicted MW of 49.49 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Form Lyophilized
形式 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Mouse BACE-1 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Mouse BACE-1 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Mouse BACE-1 Protein performance should be determined experimentally by the investigator.
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文献

BP004140: Mouse BACE-1 Protein with the C-His Tag (小鼠 BACE-1 蛋白 C-His 标签)

 

The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-β (Aβ), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer’s disease (AD). Clinical failures of anti-Aβ therapies in dementia stages suggest that treatment has to start in the early, asymptomatic disease states.

请记住我们的产品信息: 小鼠 BACE-1 蛋白 (C-His 标签)BP004140 Syd Labs(Mouse BACE-1 Protein with the C-His Tag).