Mouse ALK Protein C-hFc Tag | Syd Labs BP004154
(悉得）Syd Labs 货号：BP004154 Mouse ALK Protein with the C-hFc Tag (小鼠 ALK 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser19-Cys692.
产品参数
| 货号 | BP004154 |
|---|---|
| 产品名称 | Mouse ALK Protein C-hFc Tag | Syd Labs BP004154 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD246; |
| 物种 | Mouse |
| 来源 | The recombinant Mouse ALK Protein, (amino acids Ser19-Cys692) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | P97793 |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | Ser19-Cys692 |
| 分子量 | The recombinant Mouse ALK protein with the hFc tag at the C-terminus has a predicted MW of 101.11 kDa. Due to glycosylation, the protein migrates to 115-125 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| 形式 | Supplied as 0.22μm filtered solution in PBS, 10% Glycerol (pH 7.4). |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Mouse ALK Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Mouse ALK Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Mouse ALK Protein performance should be determined experimentally by the investigator. |
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文献
BP004154: Mouse ALK Protein with the C-hFc Tag (小鼠 ALK 蛋白 C-hFc 标签)
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in immune evasion, innate and cell-mediated immunity. New ALK-related immunotherapy approaches are demonstrating both preclinical and clinical promises.
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