[KD Validated] NQO1 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

[KD Validated] NQO1 Rabbit mAb

In stock

DTD; QR1; DHQU; DIA4; NMOR1; NMORI

SKU: A19586 分类: ,
货号 A19586
产品名称[KD Validated] NQO1 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 DTD; QR1; DHQU; DIA4; NMOR1; NMORI
基因名称 NQO1
蛋白名 NQO1
Uniprot/Swissprot ID P15559
Entrez GeneID 1728
克隆号 ARC56753
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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描述

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein’s enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer’s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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