IDO1 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

IDO1 Rabbit mAb

In stock

IDO; INDO; IDO-1

SKU: A12125 分类: ,
货号 A12125
产品名称IDO1 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 IDO; INDO; IDO-1
基因名称 IDO1
蛋白名 IDO1
Uniprot/Swissprot ID P14902
Entrez GeneID 3620
克隆号 ARC0560
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse
偶联 Unconjugated
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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描述

This gene encodes indoleamine 2,3-dioxygenase (IDO) – a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

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