Human PSMP Protein (PSM-HM201)

Human PSMP Protein (PSM-HM201)

Human PSMP Protein (PSM-HM201)

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(悉得)Syd Labs Human PSMP Protein (PSM-HM201) (catalog No. PSM-HM201) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys37-Ser139.

SKU: PSM-HM201 分类: ,

产品参数

货号 PSM-HM201
产品名称Human PSMP Protein (PSM-HM201)
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 Msmp; Psmp
物种 Human
来源 HEK293
Accession Q1L6U9
产品标签 C-hFc
生物素化 no
确定序列 Lys37-Ser139
分子量 The protein has a predicted MW of 37.9 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 Shipped at ambient temperature.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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文献

PSM-HM201: Human PSMP Protein (PSM-HM201)

PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.

Please remember our product information: Human PSMP Protein (PSM-HM201) catalog number: PSM-HM201 (悉得)Syd Labs