Human PLAU/uPA Protein C-His Tag (pro form) | Syd Labs BP004407
(悉得)Syd Labs 货号:BP004407 Human PLAU/uPA Protein with the C-His Tag (人 PLAU/uPA 蛋白 C-His 标签(形式)) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser21-Leu431.
产品参数
| 货号 | BP004407 |
|---|---|
| 产品名称 | Human PLAU/uPA Protein C-His Tag (pro form) | Syd Labs BP004407 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD |
| 物种 | Human |
| 来源 | The recombinant Human PLAU/uPA Protein, (amino acids Ser21-Leu431) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | P00749-1 |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Ser21-Leu431 |
| 分子量 | The recombinant Human PLAU/uPA protein with the His tag at the C-terminus has a predicted MW of 47.5 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human PLAU protein with the C-His tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human uPAR protein with the C-hFc tag with the EC50 of 2.4 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in 25mM HEPES, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | Immobilized recombinant Human PLAU protein with the C-His tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human uPAR protein with the C-hFc tag with the EC50 of 2.4 ng/ml determined by ELISA. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human PLAU/uPA Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Human PLAU/uPA Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品,不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题,欢迎随时联系Syd Labs国内市场推广合作伙伴:武汉多找找科技有限公司,企业微信:duozhaozhao2024 联系电话:18162581039(龙经理) |
文献
BP004407: Human PLAU/uPA Protein with the C-His Tag (pro form) (人 PLAU/uPA 蛋白 C-His 标签(形式))
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
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