Human PILRA Protein C-hFc Tag | Syd Labs BP004460
(悉得）Syd Labs 货号：BP004460 Human PILRA Protein with the C-hFc Tag (人 PILRA 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln20-Ala197.
产品参数
| 货号 | BP004460 |
|---|---|
| 产品名称 | Human PILRA Protein C-hFc Tag | Syd Labs BP004460 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | PILRA; FDF03; PILRalpha; PILR-alpha |
| 物种 | Human |
| 来源 | The recombinant Human PILRA Protein, (amino acids Gln20-Ala197) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | Q9UKJ1 |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | Gln20-Ala197 |
| 分子量 | The recombinant Human PILRA protein with the hFc tag at the C-terminus has a predicted MW of 47 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human PILRA Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human PILRA Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Human PILRA Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004460: Human PILRA Protein with the C-hFc Tag (人 PILRA 蛋白 C-hFc 标签)
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
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