Human OGN/Osteoglycin Protein C-His Tag | Syd Labs BP003227
(悉得）Syd Labs 货号：BP003227 Human OGN/Osteoglycin Protein with the C-His Tag (人 OGN/骨甘氨酸蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-terminal.It contains Pro21-Phe298.
产品参数
| 货号 | BP003227 |
|---|---|
| 产品名称 | Human OGN/Osteoglycin Protein C-His Tag | Syd Labs BP003227 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Human |
| 来源 | The recombinant Human OGN/Osteoglycin Protein, (amino acids Pro21-Phe298) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | P20774 |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Pro21-Phe298 |
| 分子量 | The recombinant Human OGN/Osteoglycin protein with the His tag at the C-terminus has a predicted MW of 32.83 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| 形式 | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human OGN/Osteoglycin Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human OGN/Osteoglycin Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human OGN/Osteoglycin Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP003227: Human OGN/Osteoglycin Protein with the C-His Tag (人 OGN/骨甘氨酸蛋白 C-His 标签)
Osteoglycin (OGN, a.k.a. mimecan) belongs to cluster III of the small leucine-rich proteoglycans (SLRP) of the extracellular matrix (ECM). In vertebrates OGN is a characteristic ECM protein of bone. The function of OGN has mainly been studied in mammals in which it regulates collagen fibrillogenesis, the efficiency of which is increased when it is processed by BMP-1/Tolloid-like metalloproteinases. OGN has a role in wound healing in the cornea, in atherosclerotic lesions and modulates myocardial integrity and remodelling. In addition, OGN enhances the neurite outgrowth promoted by insulin-like growth factor-2 and IGF binding protein-2.
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