Human LOX1 Protein N-His Tag | Syd Labs BP004634
(悉得）Syd Labs 货号：BP004634 Human LOX1 Protein with the N-His Tag (人 LOX1 蛋白 N-His 标签) is expressed from HEK293 with His tag at the N-Terminus.It contains Ser61-Gln273.
产品参数
| 货号 | BP004634 |
|---|---|
| 产品名称 | Human LOX1 Protein N-His Tag | Syd Labs BP004634 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | Ox-LDL receptor 1; LOX-1; CLEC8A; LOX1; OLR1; LOXIN; SR-E1; SCARE1; SLOX1 |
| 物种 | Human |
| 来源 | The recombinant Human LOX1 Protein, (amino acids Ser61-Gln273) fused with a His tag at the N-terminus, was produced in HEK 293 cells. |
| 产品标签 | N-His |
| 生物素化 | no |
| 确定序列 | Ser61-Gln273 |
| 分子量 | The recombinant Human LOX1 protein with the His tag at the N-terminus has a predicted MW of 25.4 kDa. Due to glycosylation, the protein migrates to 30-36 kDa under reduced condition and 60-70 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human LOX1 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | It is recommended to reconstitute the lyophilized recombinant Human LOX1 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Human LOX1 Protein performance should be determined experimentally by the investigator |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004634: Human LOX1 Protein with the N-His Tag (人 LOX1 蛋白 N-His 标签)
LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis.
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