Human LAG3/CD223 Protein C-hFc Tag | Syd Labs BP005348
(悉得）Syd Labs 货号：BP005348 Human LAG3/CD223 Protein with the C-hFc Tag (人 LAG3/CD223 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu23-Leu450.
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| 货号 | BP005348 |
|---|---|
| 产品名称 | Human LAG3/CD223 Protein C-hFc Tag | Syd Labs BP005348 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD223; FDC; LAG3; LAG-3; sLAG-3 |
| 物种 | Human |
| 来源 | The recombinant Human LAG3/CD223 Protein, (amino acids Leu23-Leu450 fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | P18627-1 |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | Leu23-Leu450 |
| 分子量 | The recombinant Human LAG3/CD223 protein with the hFc tag at the C-terminus has a predicted MW of 72.4 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human FGL1 protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human LAG3 protein with the C- hFc tag with the EC50 of 75.1 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human LAG3/CD223 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human LAG3/CD223 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human LAG3/CD223 Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
描述
BP005348: Human LAG3/CD223 Protein with the C-hFc Tag (人 LAG3/CD223 蛋白 C-hFc 标签)
LAG-3, is a protein which in humans is encoded by the LAG3 gene, which is a cell surface molecule with diverse biologic effects on T cell function. It is an immune checkpoint receptor and as such is the target of various drug development programs by pharmaceutical companies seeking to develop new treatments for cancer and autoimmune disorders.
请记住我们的产品信息: 人 LAG3/CD223 蛋白 （C-hFc 标签）BP005348 Syd Labs（Human LAG3/CD223 Protein with the C-hFc Tag）.
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