Human IL-18 R1/CD218a Protein C-His-Avi Tag | Syd Labs BP005279
(悉得）Syd Labs 货号：BP005279 Human IL-18 R1/CD218a Protein with the C-His-Avi Tag (人 IL-18 R1/CD218a 蛋白 C-His-Avi 标签) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala19-Arg329.
产品参数
| 货号 | BP005279 |
|---|---|
| 产品名称 | Human IL-18 R1/CD218a Protein C-His-Avi Tag | Syd Labs BP005279 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD218a; IL18Ra; IL18R1; IL1RRP; IL-1 R5; IL-1 Rrp; IL-18 R alpha; IL-18 R1; IL-18Ra |
| 物种 | Human |
| 来源 | The recombinant Human IL-18 R1/CD218a Protein, (amino acids Ala19-Arg329) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | AAH69575 |
| 产品标签 | C-His-Avi |
| 生物素化 | no |
| 确定序列 | Ala19-Arg329 |
| 分子量 | The recombinant Human IL-18 R1/CD218a protein with the His-Avi tag at the C-terminus has a predicted MW of 38.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| 活性 | The affinity constant of 2.38 nM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human IL-18 R1/CD218a Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human IL-18 R1/CD218a Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human IL-18 R1/CD218a Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP005279: Human IL-18 R1/CD218a Protein with the C-His-Avi Tag (人 IL-18 R1/CD218a 蛋白 C-His-Avi 标签)
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
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