Human HLA-G Free Heavy Chain Protein C-His-Avi Tag | Syd Labs BP005225
(悉得)Syd Labs 货号:BP005225 Human HLA-G Free Heavy Chain Protein with the C-His-Avi Tag (人 HLA-G 游离重链蛋白 C-His-Avi 标签) is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(C66S).
产品参数
| 货号 | BP005225 |
|---|---|
| 产品名称 | Human HLA-G Free Heavy Chain Protein C-His-Avi Tag | Syd Labs BP005225 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | HLA G antigen; sHLA-G; b2 microglobulin; HLA G; HLAG; HLA-G; MHC Class I Antigen G; MHC class Ib antigen; MHC-G; sHLA-G |
| 物种 | Human |
| 来源 | The recombinant Human HLA-G Free Heavy Chain Protein, (amino acids Gly25-Thr305(C66S)) fused with a His-Avi tag at the C-terminus, was produced in E.coli cells. |
| 产品标签 | C-His-Avi |
| 生物素化 | no |
| 确定序列 | Gly25-Thr305(C66S) |
| 分子量 | The recombinant Human HLA-G Free Heavy Chain protein with the His-Avi tag at the C-terminus has a predicted MW of 35.5 kDa. The protein migrates to 36-40 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human HLA-G Free Heavy Chain protein with the C-His-Avi tag at 2 ug/ml (100 ul/Well) on the. Dose response curve for the recombinant Anti-HLA-G Antibody protein with the C-hFc tag with the EC50 of 29.0 ng/ml determined by ELISA (QC Test). |
| Form | Liquid |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human HLA-G Free Heavy Chain Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human HLA-G Free Heavy Chain Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Human HLA-G Free Heavy Chain Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品,不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题,欢迎随时联系Syd Labs国内市场推广合作伙伴:武汉多找找科技有限公司,企业微信:duozhaozhao2024 联系电话:18162581039(龙经理) |
文献
BP005225: Human HLA-G Free Heavy Chain Protein with the C-His-Avi Tag (人 HLA-G 游离重链蛋白 C-His-Avi 标签)
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
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