Human GPVI Protein C-His Tag | Syd Labs BP004716
(悉得)Syd Labs 货号:BP004716 Human GPVI Protein with the C-His Tag (人 GPVI 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln21-Lys267.
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货号 | BP004716 |
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产品名称 | Human GPVI Protein C-His Tag | Syd Labs BP004716 |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | GPVI; Gp6; Glycoprotein 6; MGC138168 |
物种 | Human |
来源 | The recombinant Human GPVI Protein, (amino acids Gln21-Lys267) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
Accession | Q9HCN6-1 |
产品标签 | C-His |
生物素化 | no |
确定序列 | Gln21-Lys267 |
分子量 | The recombinant Human GPVI protein with the His tag at the C-terminus has a predicted MW of 28 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
活性 | Immobilized recombinant Human GPVI protein with the C-His tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-GPVI Antibody protein with the C-hFc tag with the EC50 of 4.2 ng/ml determined by ELISA. |
Form | Lyophilized |
形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
制剂 | It is recommended to reconstitute the lyophilized recombinant Human GPVI Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
运输 | The recombinant Human GPVI Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
注意事项 | Conditions of optimal recombinant Human GPVI Protein performance should be determined experimentally by the investigator. |
线下下单 | 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com或联系我们 |
描述
BP004716: Human GPVI Protein with the C-His Tag (人 GPVI 蛋白 C-His 标签)
Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands.
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