Human GPVI Protein C-His Tag | Syd Labs BP004716

Human GPVI Protein BP004716 Syd Labs

Human GPVI Protein C-His Tag | Syd Labs BP004716

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(悉得)Syd Labs 货号:BP004716 Human GPVI Protein with the C-His Tag (人 GPVI 蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln21-Lys267.

SKU: BP004716 分类: , 标签:
货号 BP004716
产品名称Human GPVI Protein C-His Tag | Syd Labs BP004716
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 GPVI; Gp6; Glycoprotein 6; MGC138168
物种 Human
来源 The recombinant Human GPVI Protein, (amino acids Gln21-Lys267) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Accession Q9HCN6-1
产品标签 C-His
生物素化 no
确定序列 Gln21-Lys267
分子量 The recombinant Human GPVI protein with the His tag at the C-terminus has a predicted MW of 28 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
活性 Immobilized recombinant Human GPVI protein with the C-His tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-GPVI Antibody protein with the C-hFc tag with the EC50 of 4.2 ng/ml determined by ELISA.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 It is recommended to reconstitute the lyophilized recombinant Human GPVI Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 The recombinant Human GPVI Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Conditions of optimal recombinant Human GPVI Protein performance should be determined experimentally by the investigator.
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描述

BP004716: Human GPVI Protein with the C-His Tag (人 GPVI 蛋白 C-His 标签)

 

Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands.

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