Human CLEC4A/DCIR Protein C-hFc Tag | Syd Labs BP004486
Syd Labs 货号：BP004486 Human CLEC4A/DCIR Protein with the C-hFc Tag (人 CLEC4A/DCIR 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln70-Leu237.
产品参数
| 货号 | BP004486 |
|---|---|
| 产品名称 | Human CLEC4A/DCIR Protein C-hFc Tag | Syd Labs BP004486 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CD367; Clec4a2; CLECSF6; DCIR; DDB27; HDCGC13P; LLIR; CLEC4A; DCIRLLIR |
| 物种 | Human |
| 来源 | The recombinant Human CLEC4A/DCIR Protein, (amino acids Gln70-Leu237) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
| 产品标签 | C-hFc |
| 生物素化 | no |
| 确定序列 | Gln70-Leu237 |
| 分子量 | The recombinant Human CLEC4A/DCIR protein with the hFc tag at the C-terminus has a predicted MW of 46.7 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Human CLEC4A protein with the C-hFc tag at 0.2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Anti-CLEC4A Antibody protein with the C-hFc tag with the EC50 of 16.0 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Human CLEC4A/DCIR Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Human CLEC4A/DCIR Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Human CLEC4A/DCIR Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP004486: Human CLEC4A/DCIR Protein with the C-hFc Tag (人 CLEC4A/DCIR 蛋白 C-hFc 标签)
Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy.
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