Human AXL Protein C-hFc Tag | Syd Labs BP004530
(悉得)Syd Labs 货号:BP004530 Human AXL Protein with the C-hFc Tag (人 AXL 蛋白 C-hFc 标签) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala26-Pro449.
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货号 | BP004530 |
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产品名称 | Human AXL Protein C-hFc Tag | Syd Labs BP004530 |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | Axl; UFO; AXL oncogene; AXL; ARK; JTK11; Tyro7; AI323647; EC 2.7.10; EC 2.7.10.1 |
物种 | Human |
来源 | The recombinant Human AXL Protein, (amino acids Ala26-Pro449) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells. |
Accession | P30530-1 |
产品标签 | C-hFc |
生物素化 | no |
确定序列 | Ala26-Pro449 |
分子量 | The recombinant Human AXL protein with the hFc tag at the C-terminus has a predicted MW of 72.6 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result. |
活性 | Immobilized recombinant Human GAS6 protein with the C-hFc tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human AXL protein with the C-hFc tag with the EC50 of 2.6 ng/ml determined by ELISA. |
Form | Lyophilized |
形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
制剂 | It is recommended to reconstitute the lyophilized recombinant Human AXL Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
运输 | The recombinant Human AXL Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
稳定性与储存 | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
注意事项 | Conditions of optimal recombinant Human AXL Protein performance should be determined experimentally by the investigator. |
线下下单 | 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com或联系我们 |
描述
BP004530: Human AXL Protein with the C-hFc Tag (人 AXL 蛋白 C-hFc 标签)
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
请记住我们的产品信息: 人 AXL 蛋白 (C-hFc 标签)BP004530 Syd Labs(Human AXL Protein with the C-hFc Tag).
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