Gemin 2 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Gemin 2 Rabbit mAb

In stock

SIP1; SIP1-delta

SKU: A19254 分类: ,
货号 A19254
产品名称Gemin 2 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 SIP1; SIP1-delta
基因名称 GEMIN2
蛋白名 GEMIN2
Uniprot/Swissprot ID O14893
Entrez GeneID 8487
克隆号 ARC2419
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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描述

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

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