Cynomolgus SOST/Sclerostin Protein C-His Tag | Syd Labs BP003946
(悉得）Syd Labs 货号：BP003946 Cynomolgus SOST/Sclerostin Protein with the C-His Tag (食蟹猴 SOST/硬化蛋白 C-His 标签) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln69-Tyr258.
产品参数
| 货号 | BP003946 |
|---|---|
| 产品名称 | Cynomolgus SOST/Sclerostin Protein C-His Tag | Syd Labs BP003946 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Cynomolgus |
| 来源 | The recombinant Cynomolgus SOST/Sclerostin Protein, (amino acids Gln69-Tyr258) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | XP_005584428.2 |
| 产品标签 | C-His |
| 生物素化 | no |
| 确定序列 | Gln69-Tyr258 |
| 分子量 | The recombinant Cynomolgus SOST/Sclerostin protein with the His tag at the C-terminus has a predicted MW of 22.58 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result. |
| 活性 | Immobilized recombinant Cynomolgus SOST protein with the C-His tag at 0.2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-SOST Antibody protein with the C-hFc tag with the EC50 of 10.0 ng/ml determined by ELISA. |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Cynomolgus SOST/Sclerostin Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Cynomolgus SOST/Sclerostin Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Cynomolgus SOST/Sclerostin Protein performance should be determined experimentally by the investigator. |
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文献
BP003946: Cynomolgus SOST/Sclerostin Protein with the C-His Tag (食蟹猴 SOST/硬化蛋白 C-His 标签)
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
请记住我们的产品信息: 食蟹猴 SOST/硬化蛋白 （C-His 标签）BP003946 Syd Labs（Cynomolgus SOST/Sclerostin Protein with the C-His Tag）.