Chimeric HLA-A*02
Chimeric HLA-A*02
Chimeric HLA-A*02
Chimeric HLA-A*02
Chimeric HLA-A*02
Chimeric HLA-A*02

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein (MHC-HM413T)

Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) BP003971 Syd Labs Biotinylated Cynomolgus PADI4 Protein N-His Tag (Primary Amine Labeling) | Syd Labs BP003971
Proteinase K Solution, PCR Grade (20 mg/ml): MB112 Syd Labs Proteinase K Solution, PCR Grade (20 mg/ml)
Chimeric HLA-A*02

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein (MHC-HM413T)

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(悉得）Syd Labs Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein (MHC-HM413T) (catalog No. MHC-HM413T) isisassembled by biotinylated monomer and streptavidin.It contains Gly25-Thr206(Human HLA-A*02:01 α1&α2)&Asp207-Glu299(Mouse H-2Ld α3), Ile21-Met119(B2M) and CLGGLLTMV peptide.

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Syd Labs & Antibody
SKU： MHC-HM413T 分类： ,

产品参数

货号 MHC-HM413T
产品名称Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein (MHC-HM413T)
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; RING12
物种 Human&Mouse
来源 HEK293
Accession A0A140T913(Human HLA-A*02:01 α1&α2)&P01897(Mouse H-2Ld α3)&P61769(B2M)&CLGGLLTMV
产品标签 C-His-Avi
生物素化 no
确定序列 Gly25-Thr206(Human HLA-A*02:01 α1&α2) & Asp207-Glu299(Mouse H-2Ld α3), Ile21-Met119(B2M) and CLGGLLTMV peptide
分子量 The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
Form Lyophilized
形式 Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
制剂 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
纯度 >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
内毒素 Less than 1 EU per ug of protein as determined by LAL method.
运输 Shipped at ambient temperature.
稳定性与储存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution.
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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文献

MHC-HM413T: Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein (MHC-HM413T)

The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2.

Please remember our product information: Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein (MHC-HM413T) catalog number: MHC-HM413T (悉得）Syd Labs